Deoxycholic Acid Injections for Submental Fat Reduction

The deoxycholic acid injection is indicated for improvement in the appearance of moderate to severe fullness associated with submental fat, also called “double chin,” in adults. Deoxycholic acid is injected into the fat under the chin. Multiple treatments are usually required and will be given at least 1 month apart.
For adults only: 18-65 years old.
The number of treatment sessions needed for the best aesthetic results depends on the patient’s response to the therapy and the patient’s expectations. Up to 6 treatments spaced at intervals of no less than 1 month apart are recommended. For more information about under chin fat reduction please visit our beauty spa clinic in Richmond Hill.


  • Patients who are hypersensitive to this drug or to any ingredient in the formulation or component of the container
  • The presence of infection in the treatment area
  • Pregnancy, breastfeeding
  • Serious heart disease
  • Renal or hepatic impairment/disease
  • Uncontrolled diabetes mellitus

Deoxycholic acid injection (ATX-101) is the only injectable drug for the reduction of submental fat that is approved in the United States and Canada.

Side Effects

  • Swelling
  • Bruising
  • Pain
  • Numbness
  • Redness
  • Areas of hardness in the treatment area

These side effects typically resolve themselves without treatment and do not usually result in patients stopping treatment. Deoxycholic acid injections can also cause:

  • Tingling
  • Nodule
  • Itching
  • Skin tightness
  • Headache.

Less common potential side effects include nerve injury. Deoxycholic acid injections could cause nerve injury in the area of the jaw resulting in an uneven smile or facial muscle weakness

Typically, these are all resolved without treatment and do not require patients to stop treatment.

Deoxycholic acid injections can temporarily cause trouble with swallowing (very rare, and probably due to neck swelling), superficial skin erosions, and small patches of hair loss in the beard area. There is a possibility of an unsatisfactory result. The procedure may also result in more noticeable platysma bands, unacceptable visible deformities, or asymmetry in the treatment area.

Our clients visit our clinic from all over the GTA, including Richmond Hill, Toronto, Vaughan, Markham, Aurora, Newmarket, Mississauga, Oakville, Brampton, Milton, Barrie, and more.

*Individual results may vary